Boswellia and Berberine have both been used extensively in clinical trials with colitis and Crohn's as an anti-inflammatory. As stated below:
"Considering both safety and efficacy of Boswellia serrata extract H15 it appears to be superior over mesalazine in terms of a benefit-risk-evaluation."
Do an Internet or PubMed search for the articles. In the meantime, here are a few to get you started:
1. Effects of Boswellia serrata in mouse models of chemically induced colitis.
Kiela PR, Midura AJ, Kuscuoglu N, Jolad SD, Solyom AM, Besselsen DG, Timmermann BN, Ghishan FK.
Dept. of Pediatrics, Children's Research Center, Univ. of Arizona, 1501 N. Campbell Ave., Tucson, AZ 85724, USA.
Am J Physiol Gastrointest Liver Physiol. 2005 Apr;288(4):G798-808. Epub 2004 Nov 11.
Abstract:
The goal of this study was to evaluate the effectiveness of boswellia extracts in controlled settings of dextran sulfate- or trinitrobenzene sulfonic acid-induced colitis in mice.
PMID: 15539433
2. [Therapy of active Crohn disease with Boswellia serrata extract H 15] [Article in German]
Gerhardt H, Seifert F, Buvari P, Vogelsang H, Repges R.
Colitis-Crohn-Ambulanz, I. Medizinische Klinik, Klinikum Mannheim der Universitat Heidelberg.
Z Gastroenterol. 2001 Jan;39(1):11-7.
Abstract:
The purpose of this clinical trial was to compare efficacy and safety of the Boswellia serrata extract H15 with mesalazine for the treatment of active Crohn's disease. CONCLUSIONS: The study confirms that therapy with H15 is not inferior to mesalazine, which can be interpreted as evidence for the efficacy of H15 according to the state of art in the treatment of active Crohn's disease with Boswellia serrata extract, since the efficacy of mesalazine for this indication has been approved by the health authorities. Considering both safety and efficacy of Boswellia serrata extract H15 it appears to be superior over mesalazine in terms of a benefit-risk-evaluation.
Publication Types: Clinical Trial, Randomized Controlled Trial
PMID: 11215357
3. Effects of gum resin of Boswellia serrata in patients with chronic colitis.
Gupta I, Parihar A, Malhotra P, Gupta S, Ludtke R, Safayhi H, Ammon HP.
Department of Medicine, Medical College Jammu, J&K, India.
Planta Med. 2001 Jul;67(5):391-5.
Abstract:
Patients studied here suffered from chronic colitis characterized by vague lower abdominal pain, bleeding per rectum with diarrhoea and palpable tender descending and sigmoid colon. This study shows that a gum resin preparation from Boswellia serrata could be effective in the treatment of chronic colitis with minimal side effects.
Publication Types: Clinical Trial, Randomized Controlled Trial
PMID: 11488449
4. Effects of Boswellia serrata gum resin in patients with ulcerative colitis.
Gupta I, Parihar A, Malhotra P, Singh GB, Ludtke R, Safayhi H, Ammon HP.
Department of Medicine, Govt. Medical College, Jammu, J&K, India.
Eur J Med Res. 1997 Jan;2(1):37-43.
Abstract:
In patients suffering from ulcerative colitis grade II and III the effect of Boswellia serrata gum resin preparation (350 mg thrice daily for 6 weeks) on stool properties, histolopathology and scan microscopy of rectal biopsies, blood parameters including Hb, serum iron, calcium, phosphorus, proteins, total leukocytes and eosinophils was studied. All parameters tested improved after treatment with Boswellia serrata gum resin, the results being similar compared to controls: 82% out of treated patients went into remission; in case of sulfasalazine remission rate was 75%.
Publication Types: Clinical Trial, Controlled Clinical Trial
PMID: 9049593
take care,
Jini










